脉压水平与冠状动脉病变的相关性研究

Relationship between the pulse pressure and the lesion severity of coronary artery

目的:探讨脉压水平与冠状动脉病变严重程度的相关性。方法:根据257例冠脉造影阳性患者的脉压水平,分为脉压≤65 mmHg(1 mmHg=0．133 kPa)和>65 mmHg两组;又按AHA及ACC冠状动脉粥样硬化病变的分类方法,对冠脉病变程度进行分类。然后统计不同组别间冠脉各种病变的发生率,并作出统计学分析。结果:两组间A、 B型及单支、双支病变发生率相似．但脉压>65 mmHg组的C型及三支病变发生率明显高于脉压≤65 mmHg组的 (P<0．05);且脉压与病变狭窄度、长度呈正相关关系(r=0．356、=0．298,P<0．05)。结论:脉压与冠状动脉病变呈正相关,在临床治疗时应注意对脉压的控制。

Objective： To study the relationship between the level of the pulse pressure （PP） and the severity of the lesion of the coronary artery. Methods： A total of 257 patients with a positive coronary angiography were divided into two groups according to the level of the pulse pressure： one group with the PP≤65 mmHg and the other group with the PP〉65 mmHg. The severity of the lesion of the coronary artery were classified with AHA/ACC typing, Results： There was no significant difference in the incidence of the lesion of type-A and B and the uni-vessel, bi-vessel lesion of coronary artery between the two groups, but the incidence of the lesion of the type-C and tri-vessel lesion in the group with PP〉65 mmHg was higher than those in the group with PP〉65 mmHg （P〈0.05）. Moreover the level of the PP positively correlates with stenosis degree and length of the coronary artery lesion （r=0. 356, =0. 298, P〈 0.05）. Conclusion： The level of the PP positively correlates with the coronary artery lesion. Great importance shall be attached to the controlling of the PP in patients with coronary artery diseases.