薄层色谱法在Gemini阳离子表面活性剂制备中的应用

Application of Thin Layer Chromatography of Synthesis Gemini Cationic Surfactant

以十八烷基二甲基胺(OTA)和环氧氯丙烷(EPIC)为反应原料,经过环氧中间体十八烷基失水甘油基二甲基氯化铵(OGDMAC)合成了Gemini阳离子表面活性剂1,3二(十八烷基二甲基氯化铵)异丙醇。利用薄层色谱法与经典化学滴定法相结合,对其合成及纯化过程进行跟踪,展示了薄层色谱法在Gemini阳离子表面活性剂制备中的应用。

The Gemini cationic surfactant 1,3-dis（ n-octadecyldimethylammonium chlofide）-isopropanol was prepared using n-octadeeyldimethylamine （ OTA ） and epiehlorohydrin （ EPIC ） through the middle product n- octadecylglycidyldimethylammonium chloride （OGDMAC）. Thin layer chromatography （TLC） and the usual titration method were used to trace the synthesis and the purity of the Gemini cationic surfactant, and all of these have revealed the important value of TLC in the preparation of Gemini cationic surfactant.