摘要
目的:了解复方甘草酸苷对慢性重症肝炎患者肝脏储备功能的影响。方法:100例慢性重症肝炎患者分为复方甘草酸苷组(治疗组50例。静滴复方甘草酸苷80 mL/d,连续60 d)和肝安组(对照组50例。静滴肝安250 mL/d,连续60 d);60d后检测两组肝功能指标及肝脏储备功能的变化。结果:治疗组肝脏储备功能较治疗前明显升高(P<0.05),与对照组比无统计学意义(P>0.05);两组肝功能指标均有改善(P<0.05)。结论:复方甘草酸苷能显著减轻肝脏损伤程度,提高其储备功能,且耐受性良好,无明显不良反应。
Objective: To understand the effect of compound glycyrrhizin on hepatic function of reserve in patients with chronic fulminate hepatitis. Methods: One hundren patients with chronic fulminate hepatitis were divided into treatment group(50 cases were injected chronic fulminate hepatitis of 80 mL iv. drip, once a day, 60 days continuously)and control group(50 cases were injected 15AA of 250 mL iv. drip, once a day, 60 days continuously). The changes of the liver function indices and the hepatic function of reserve were detenninated 60 days after treatment. Results: Sixty days after treatment, the hepatic function of reserve in treatment group was higher( P 〈 0.05). There was no statistically significance in hepatic function of reserve in treatment group, compared with control group. The liver function indices between two groups were improved(P 〈 0.05). Conclusion: The compound glycyrrhizin can greatly reduce the damage of liver,and raise the hepatic function of reserve. There is a good toleration, and no obvious side effects have been found.
出处
《汕头大学医学院学报》
2006年第2期96-97,共2页
Journal of Shantou University Medical College
关键词
慢性重症肝炎
复方甘草酸苷
肝脏储备功能
chronic fulminate hepatitis
compound glycyrrhizin
hepatic function of reserve