腹腔镜卵巢楔切治疗难治性多囊卵巢综合征不孕的临床观察

Clinical Observation of Laparoscopic Ovarian Wedge Resection in the Treatment of Clomiphene-resistant Polycystic Ovary Syndrome

目的:探讨腹腔镜卵巢楔切治疗难治性多囊卵巢综合征引起不孕的疗效。方法:在腹腔镜下行卵巢楔切或加打孔术治疗51例难治性多囊卵巢综合征患者,术后观察月经恢复及妊娠情况。结果:术后排卵率67.4%,累积妊娠率63.9%,流产率2.8%,异位妊娠率2.8%,多胎妊娠率2.8%。结论:腹腔镜手术是治疗难治性多囊卵巢综合征不孕的简单、疗效肯定的好方法,应在最佳妊娠时间内积极治疗。

Objective： To evaluate the efficacy of laparoscopic ovarian wedge resection and electrocautery in clomiphene-resistant polycystic ovary syndrome（PCOS）. Methods： A total of 51 PCOS patients who had no response to ovulation-inductive drugs were treated by ovarian wedge resection and electrocautery via laparoscopy. After surgery, the menstrual pattern and pregnancy outcome were observed. Results： The ovulation rate, cummulative pregnancy rate, abortion rate, ectopic pregnancy rate and multiple pregnancy rate were 67.4%, 63.9%, 2.8%, 2.8%, and 2.8%, respectively. Conclusion： Laparoscopic ovarian wedge resection and electrocautery are rather simple and effective methods for the treatment of PCOS. It is very recommendable to take active measures in the best pregnant time after surgery.