摘要
We investigated whether nonsteroidal antiinflammatory drug use was associated with a lower risk for Parkinson’s disease (PD) in a large cohort of US men and women. PD risk was lower among ibuprofen users than nonusers. Compared with nonusers, the relative risks were 0.73 for users of fewer than 2 tablets/week, 0.72 for 2 to 6.9 tablets/week, and 0.62 for 1 or more tablets/day (ptrend = 0.03). No association was found between the use of aspirin, other nonsteroidal antiinflammatory drugs, or acetaminophen and PD risk. The results suggest that ibuprofen use may delay or prevent the onset of PD.
We investigated whether nonsteroidal antiinflammatory drug use was associated with a lower risk for Parkinson＇s disease （PD） in a large cohort of US men and women. PD risk was lower among ibuprofen users .than nonusers. Compared with nonusers, the relative risks were 0. 73 for users of fewer than 2 tablets/week, 0. 72 for 2 to 6.9 tablets/week, and 0. 62 for 1 or more tablets/day （ptrend = 0. 03）. No association was found between the use of aspirin, other nonsteroidal antiinflammatory drugs, or acetaminophen and PD risk. The results suggest that ibuprofen use may delay or prevent the onset of PD.
出处
《世界核心医学期刊文摘（神经病学分册）》
2006年第5期16-16,共1页
Digest of the World Core Medical Journals:Clinical Neurology
