原发性回盲肠恶性淋巴瘤8例

Eight Cases with Primary Ileum Cecum Malignant Lymphoma

目的探讨原发性回盲肠恶性淋巴瘤的临床特点、诊断及治疗。方法对小儿原发性回盲肠恶性淋巴瘤8例的临床特征、影像学表现、术中发现及病理资料进行回顾性分析。结果患儿8例均行根治性手术,术后辅以化疗和放疗2例,1例生存4年,1例生存1年失访;余6例患儿,2例生存2年仍在随访中,生存1、0.5年死亡各1例,另外2例失访。病理及免疫组织化学检查结果:CK(-),CD20(+),CD45RO(-),MPO(-),Ki67>60%、Ki67>75%各4例。结论原发性回盲肠恶性淋巴瘤临床表现复杂多样而缺乏特异性,组织病理学检查是确诊本病的主要手段,早期根治手术辅以化疗和放疗是主要治疗方法。

Objective To study the clinical characteristics, diagnosis and treatment of 8 children with primary ileum cecum malignant lymphoma. Methods Retrospective analysis on the clinical and pathology materials of 8 children with primary ileum cecum malignant lymphoma was performed. Resdts Primary ileum cecum malignant lymphom＇s clinical experience had no characteristic, and radical operation was main treatment method. Chemothereapy got well to some extents. Pathology and immunity tissue chemical were B cell malignant lymphoma. Conclusions Child primary ileum cecum malignant lymphoma lack specific manifestations, and histopathology is main diagnosis methods. They have good response to binding treatment of early operation and chemothereapy.