急诊胆囊炎不同手术方式对机体凝血功能的影响

Influences of Two Modus Operandi in Acute Cholecystitis on Coagulative Function

目的探讨急诊胆囊炎不同手术方式对机体凝血功能的影响。方法随机选择急诊腹腔镜胆囊切除术(LC)患者32例和急诊开腹胆囊切除术(OC)患者30例,术前1h,术后1、24、72h静息空腹采血检测凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶凝固时间(TT)、纤维蛋白原(Fg)及血小板计数(PLT)值,比较两组患者上述指标变化。结果急诊LC组术后PT、APTT、TT、Fg及PLT值均有不同程度的改变,但与急诊OC组相应指标比较差异无统计学意义。结论急诊LC和急诊OC术后血液均处于高凝状态,二者对机体凝血功能的影响无明显不同。

Objective To study the influences of two modus operandi in acute cholecystitis on coagulative function. Methods Thirty and two patients with acute cholecystitis underwent laparoscopic cholecystectormy and 30 patients with acute cholecystitis underwent open cholecystectormy were randomized. Blood samples were collected while resting and empty stomach, PT, APTT, TT, FBG and PLT levels were assessed preoperatively and 1h, 24h, 72h postoperatively. All the parameters were compared between the two groups. Results The levels of PT, APTT, TT, Fg and PLT changed postoperatively in LC group, but no difference compared with OC group. Conclusion Emergency LC and emergency OC induces up-regulation of coagulation system and has less influence on blood coagulation.