锌参与下水相介质中双酮的选择性烯丙基化反应

Selective Allylation of Diketones in the Presence of Water by Allyl Bromide and Metallic Zinc

本文报道锌参与下水相介质中对称双酮及混合双酮的选择性烯丙基化反应的研究。同时提供了它们在有机合成中应用的一个实例——雄甾烯二酮的选择性单烯丙基化。

Selective allylation of the linear, cyclic and mixed diketones in the presence of water by allyl bromide and metallic zinc have been successfully achieved. An example of practicable application on organic synthesis, monoallylation of androstendione, has been suggested.