摘要
细胞免疫组织化学及分子遗传学技术的发展,对以往诊断为恶性组织细胞增多症、组织细胞性淋巴瘤等组织细胞肿瘤,进行了重新认识,并证明大多数病例为T细胞、NK细胞或B细胞淋巴瘤以及噬血细胞综合征。本文介绍新的WHO组织细胞/树突状细胞肿瘤分类、形态学和免疫组织化学的诊断要点、临床表现特征、治疗及预后。噬血细胞综合征是非肿瘤性、巨噬细胞增殖、活化伴有噬血细胞吞噬现象的临床病理综合征,并介绍了噬血细胞综合征的分类、诊断标准和治疗原则。重新认识组织细胞和树突状细胞肿瘤将有助于提高本病的诊治水平、改善预后。
With the development of new immunophenotypic and molecular genetic technique, histiocytic tumors can be correctly diagnosed. Reassessment of formerly considered histiocytic tumors disclosed that the most cases were T cell, NK cell, or B cell lymphomas and hemophagocytic syndrome or others. In this paper, the classification, diagnostic criteria, treatment and prognosis of histiocyte/dendritic cell neoplasms were described. The term hemophagocytie lymphohistiocytosis is a reactive non - malignant clinicopathological syndrome. The clinical manifestation, diagnostic criteria, treatment and prognosis of hemophagocytie syndrome have also been discussed here.
出处
《癌症进展》
2006年第2期152-156,130,共6页
Oncology Progress
关键词
组织细胞
树突状细胞肿瘤
噬血细胞综合征
分类
诊断
治疗
histiocyte/dendritic cell tumor hemophagocytic syndrome classification diagnosis treatment
