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A Dynamic Programming Algorithm for the κ-Haplotyping Problem 被引量:3

A Dynamic Programming Algorithm for the κ-Haplotyping Problem
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摘要 The Minimum Fragments Removal (MFR) problem is one of the haplotyping problems: given a set of fragments, remove the minimum number of fragments so that the resulting fragments can be partitioned into k classes of non-conflicting subsets. In this paper, we formulate the κ-MFR problem as an integer linear programming problem, and develop a dynamic programming approach to solve the κ-MFR problem for both the gapless and gap eases. The Minimum Fragments Removal (MFR) problem is one of the haplotyping problems: given a set of fragments, remove the minimum number of fragments so that the resulting fragments can be partitioned into k classes of non-conflicting subsets. In this paper, we formulate the κ-MFR problem as an integer linear programming problem, and develop a dynamic programming approach to solve the κ-MFR problem for both the gapless and gap eases.
出处 《Acta Mathematicae Applicatae Sinica》 SCIE CSCD 2006年第3期405-412,共8页 应用数学学报(英文版)
基金 Supported by the National Natural Science Foundation of China (No. 60503004, No. 10471141). Thc authors gratefully acknowledge the support of K.G.Wang Education Foundation of Hong Kong.
关键词 Integer programming dynamic programming κ-haplotyping SNP Integer programming, dynamic programming, κ-haplotyping, SNP
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