急性冠脉综合征合并糖尿病患者冠状动脉狭窄程度与血脂关系的研究

The Correlation between Blood Lipid Profile and Coronary Artery Stenosis in Patients with Acute Coronary Syndrome and Diabetes Mellitus

目的:探讨急性冠脉综合征(ACS)合并糖尿病(DM)患者冠状动脉狭窄程度与血脂代谢异常的关系。方法:将临床确诊为ACS合并DM且已行冠状动脉造影的68例患者,根据冠状动脉造影结果分为三组,即冠脉轻度、中度和重度狭窄组,分别检测三组患者的总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及载脂蛋白A1(apoA1)、载脂蛋白B(apoB)。结果:三组患者的TG、LDL-C、HDL-C及apoB水平差异有显著性意义。结论:TG、LDL-C、HDL-C及apoB水平在ACS合并DM患者冠状动脉病变的发生及受损程度上起着重要作用,脂代谢异常可能影响冠状动脉病变程度。

Objective： To explore the relation between the degree of coronary artery stenosis and blood lipid of ACS with DM. Methods： Based on coronary angiography 68 patients were diagnosed as diabetes with ACS. They were divided into the 3 groups, minor steonsis group, middle steonsis group and sever steonsis group. Analysed the relation between the degree of coronary artery stenosis and blood lipid. Results： The riG, LDL - C of middle and severe stenosis group were higher than those of the minor stenosis group, while HDL - C of middle and severe stenosis group was much lower than those of the light group.Conclusion： riG, LDL - C, HDL - C and apoB may a play very important role in coronary artery disease. Dyslipemia may influence the severity of coronary artery stenosis.