妊娠梅毒63例临床分析

Clinical Analysis of 63 Pregnant Women with Syphilis

目的研究妊娠梅毒的发病率,分析其发病特点,并探讨其防治方法,以降低先天性梅毒儿的发病率。方法63例经血清学检查确诊为妊娠梅毒孕妇,根据其确诊孕周数分组,比较各组孕妇妊娠结局、围生儿预后及新生儿梅毒发生情况,分析梅毒的治疗与先天梅毒儿发病率之间的关系。同时将孕妇分为流动人口组与长期居住组,比较其发病率。结果妊娠梅毒的发生率为4.5‰,其中流动人口占61.9%。不同孕周先天梅毒的发病率分别为:13～27周占12.5%,28～36周占27.3%,37周以上占42.9%。结论妊娠梅毒的发病率有逐年上升的趋势。降低妊娠梅毒及先天梅毒儿的发病率,关键在于加强婚前检查及早孕检测。

Objective To study the morbidity of pregnant women with syphilis. To analyse the characteristics and examine the methods for the prevention and cure of congenital syphilis. Method According to the gestational week of final diagnosis, 63 pregnant women with syphilis were divided into various groups. The pregnant outcomes, prognosis of neonates and congenital syphilis were then compared. The pregnant women were also divided into two groups according to their mobility status. Result The morbidity of pregnant women with syphilis is 4.5‰, in which 61.9% are mobile population. The incidence of cognitional syphilis at 13-17 weeks, 28-36 weeks, and over 37 weeks of gestation was 12.5%, 27.3% and 42.9%, respectively.Conclusion There was a tendency of increase in syphilis in pregnant women over the past few years. Strengthening the pre-marital consultation and medical checkup programme may reduce the incidence of congenital syphilis in pregnant women.