重症急性胰腺炎的治疗现状

Therapy Status of Severe acute Pancreatitis

重症急性胰腺炎（Severe acute pancreatitis，SAP）是一种发病急、病情进展变化快，并发症复杂的急性腹痛性疾病。其治疗现状包括尽早诊断，尽早采用非手术综合措施治疗：抗休克，复苏器官功能；代谢调理，营养支持；血液滤过去除促炎症细胞因子，降低过度的炎症反应，免疫疗法相关物的应用；降酶，抑酶，阻止胰酶的损害作用；区域性动脉灌注给药，提高胰腺循环中的血药浓度，充分的发挥药物的作用：合理使用抗生素及其他药物，防止毒副作用加重病情，警惕二重感染；当重症监护治疗病情进展时，择机外科手术干预：后期出现局部或全身并发症，选择恰当的手术治疗。

Severe acute pancreatitis, SAP is one of the acute abdominal pain diseases, with acu-onset 、 fast progression of pathogenetic condition and multiple complication. The therapy status included： early diagnosis and early treatment deploying nonoperative synthesized measures such as countershock, resuscitation of organic function, regulation of metabolism, nutritional support, eliminating chemotaetic cytokines and lowering the excessive inflammatory reaction by hemofiltration, application of immunotherapy, preventing damages of pankrin through kata-pankrin or ant-pankrin, increasing drug level by Regional arterial infusion, rational use of antibiotics and other drugs to prevent toxic side effect, vigilance of dual infection. While undergoing intensive care, the patients are getting worse. The surgery should be operated when chose a suitable time. And choose a pertinence operation if the patient appears part or system complication.