钛合金和钴铬合金表面白色念珠菌粘附的研究

Adhesion of Oral Candida Albicans on Ti-6Al-4V Alloy and Chromium-Cobalt Alloy

目的比较钛合金(Ti-6Al-4V)和钴铬合金(Chromium-Cobaltalloy)表面白色念珠菌粘附能力的大小,研究表面粗糙度与细菌粘附的关系。方法将不同表面粗糙度的钛合金和钴铬合金试件进行白色念珠菌体外粘附试验,采用菌落形成计数法测定试件表面的细菌粘附量。结果各钛合金试件组的细菌粘附量均少于相同表面粗糙度的钴铬合金试件组,两种金属试件表面的细菌粘附量均随表面粗糙度的增大而增加。结论钛合金较钴铬合金更能减少由白色念珠菌引起的义齿性口炎等并发症,同时修复体表面严格的研磨抛光也能有效减少这些并发症。

objective This study compared the adhesion of Candida albicans to Ti-6Al-4V alloy and Chromium- Cobalt alloy in vitro, and studied the correlation between surface roughness and bacteria adhesion. Methods The quantification of the attached bacteria on the surfaces of the material was assayed by means of clone forming unit （CFU） method of 24,48,and 168 hours after the bacteria were seeded onto the Ti-6Al-4V alloys and Chromium-Cobalt alloys of the different surface roughness. Results The quantification of the attached bacteria on the surfaces of Ti-6Al-4V alloy is less than Chromium-Cobalt alloy, with the increase of roughness, bacteria adhered on two kinds of sample improved in amount.Conclusion Compared with Chromium-Cobalt alloy, Ti-6Al-4V alloy can decrease the complication caused by attached bacteria, further more, grinding and polishing the surface of the prothesis can reduce the complication caused by attached bacteria.