全自动膜片钳放大器快电容补偿技术改进

The Improvement of C-Fast Transient Cancellation In Automatic Patch-Clamp Amplifier

介绍了膜片钳放大器中快电容产生的机理,根据新的快电容电气模型设计出相应的补偿硬件电路和软件算法,并通过计算机实现自动补偿。实验结果表明,该补偿技术能够快速有效的消除快电容瞬态电流,提高实验的操作效率和数据准确性。

This paper describes the principle of the fast - capacitance in the patch - clamp amplifier, designs the C - Fast transient cancellation circuitry and algorithms according to the new electrical model, and realizes the automatic adjustment of the circuitry through the computer. The test result of the design demonstrates that the compensation technology could speed up the C - Fast transient cancellation effectively and improve the efficiency and the precision of the experiment.