脉压差、载脂蛋白AI/B比值对颈动脉硬化者的意义

Significance of pulse pressure and apolipoprotein AI/B ratio in patients with carotid atherosclersis.

目的评价脉压差、载脂蛋白AI/B比值与颈动脉硬化的关系。方法根据超声学检查结果将颈动脉硬化患者分为3组,即正常组、血管增厚组、斑块组,分析比较每组脉压差、载脂蛋白AI/B比值,并进行统计学处理。结果脉压差在斑块组中有所增大(P<0.05);而载脂蛋白AI/B比值在增厚组降低(P<0.05),在斑块组明显降低(P<0.01)。结论脉压差、载脂蛋白AI/B比值与颈动脉硬化有明显的相关性,可能参与动脉粥样硬化的形成和发展。

Objective To assess the correlation of carotid arteriosclerosis with plasma apolipoprotein AI/B ratio and pulse pressure. Methods By the ultrasound echocardiography, the patients were divided into three groups： normal group,vascular hypertrophy group and vascular plaque group. The plasma apolipoprotein AI/B ratio and pulse pressure were statistically compared. Results The pulse pressure was significantly increased in plaque group （ P 〈 0.05 ）, the apolipoprotein AI/B ratio was lower in hypertrophy group （ P 〈 0.05 ）, and was obviously reduced in plaque group （P 〈 0.01 ）. Conclusion The pulse pressure and apolipoprotein AI/B ratio are related to carotid atherosclersis, which may take part in the forming and developing of atherosclerosis.