输卵管切除术对体外受精-胚胎移植中控制性超促排卵的影响

Effects of Salpingectomy on Superovulation in Vitro Fertilization Embryo Transfer Program

目的:探讨输卵管切除术对体外受精-胚胎移植(IVF-ET)周期超促排卵中卵巢反应性的影响。方法:选择因异位妊娠行一侧输卵管切除、双侧输卵管切除的患者以及双侧输卵管未切除的管性不孕患者,观察在IVF-ET中卵巢对控制性超排卵的反应。结果:3组患者年龄、促性腺激素用量、获卵数、受精数以及妊娠率差异无统计学意义。单侧输卵管切除的患者中输卵管切除侧卵巢获卵数少于对侧,但差异无统计学意义。结论:输卵管切除术对IVF-ET周期中卵巢反应性以及妊娠率无明显影响。输卵管积水患者拟行IVF-ET前预防性切除输卵管是可行的。

Objective： To investigate the effects of salpingectomy on ovary in vitro fertilization embryo transfer program （IVF-ET）. Methods： The ovarian responses to superovulation were evaluated in patients with unilateral/bilateral salpingectomy for ectopic pregnancy and patients with tubal infertility with existing salpinx. Results： There was no significant difference of age, hormone dosage, retrieved oocytes, fertilized oocytes and the pregnancy rates among 5 groups. The number of retrieved oocytes in the operated side was lower than that in contralateral side in unilateral salpingectomy, and there was no significant difference between them, Conclusion： Salpingectomy has no significant effect on ovarian response during [VF-ET and pregnancy rate, and prophylatic laparoscopic salpingectomy is acceptable before IVF in hydrosalpinges patients.