酮症起病糖尿病患者的临床特点观察

Clinical observation of diabetic patients with unprovoked ketosis

目的探讨自发酮症起病的糖尿病患者的临床特点与分型。方法29例自发酮症起病的糖尿病患者根据BMI被分为非肥胖组(19例)和肥胖组(10例)。比较两组在年龄、性别、起病情况、胰岛功能、血糖和血脂方面的差异。结果肥胖组与非肥胖组比较,发生酮症或酮症酸中毒时的胰岛素缺乏程度相对较轻,血脂较高。结论自发酮症起病的肥胖糖尿病患者具有不同于1型糖尿病的临床特征,建议考虑独立分型。

Objective To study the clinical characteristics and classification of diabetics with unprovoked ketosis. Methods 29 diabetic patients with unprovoked ketosis were divided into two groups according to BMI：normal body weight group （19 ones） and obese group （10 ones）. The clinical characteristics including age, sex, mode of presentation, islet beta-cell function,glucose,serum triglyceride and cholesterol were compared between the two groups. Results Compared with the normal weight group,the patients in obese group had less severe insulin deficiency when ketosis or ketoacidosis occurred. And their serum triglyceride and cholesterol were higher. Conclusions The clinical characteristics of obese diabetic patients with unprovoked ketosis were different from those of type one diabeticpatients. And a new type should be considered.