超急性及急性脑梗塞的磁共振弥散成像

<TITLE>MRI DIFFUSION WEIGHTED IMAGING IN SUPER-ACUTE AND ACUTE CEREBRAL INFARCTION

目的评价磁共振弥散加权成像在老年人超急性、急性脑梗塞中的应用及与常规磁共振序列、CT之间的比较。方法共收集61例疑似超急性、急性脑梗塞患者(平均年龄70岁),在发病24h内进行磁共振T1WI、T2WI、水抑制序列、弥散加权扫描以及CT扫描。结果共有36例患者确诊为超急性或急性脑梗塞,弥散加权序列准确显示了35例,敏感性为97%、特异性为99%;水抑制序列加T2WI为56%、57%,CT为44%、48%。结论弥散加权对于24h内超急性、急性期脑梗塞的显示明显优于常规磁共振序列及CT,并且可以很好地区分急性与慢性梗塞病灶。

Objective To evaluate the usefulness of MRI Diffusion-Weighted-Imaging in the diagnosis of senile super-acute and acute cerebral infarction. And to compare its value with conventional MRI sequences and CT. Methods Sixty-one cases with suspected super-acute or acute cerebral infarction were scanned using MR1 T1W1, T2W1, FLA1R, DWI and CT. The mean age of patients was 70 years. All patients were examined within twenty-four hours from the onset of symptoms. Results Within all patients, thirty-six cases were verified as having super-acute or acute infarction by clinical and MRI follow-ups. DWI made a correct diagnosis in thirty-five cases. Its sensitivity was 97% and specificity 99%; while sensitivity and specificity of FLAIR plus T2WI were 56%,57% and those of CT were 44%, 48% respectively. Conclusions MRI diffusion weighted imaging is superior to conventional MRI sequences and CT in displaying super-acute and acute cerebral infarctions and in differentiating acute from chronic lesions.