一株Streptosporangium sp.的次生代谢产物的研究

Studies on the Secondary Metabolism of Streptosporangium sp.

通过对Streptosporangium sp.菌株发酵液的初步分离纯化,得到二个化合物,由波谱数据解析鉴定其结构分别为YXJE1(1),7,4′-二羟基黄酮(2)。其中化合物1是新化合物。活性实验证明化合物1,2具有一定的抑制乙酰胆碱酯酶活性。

Two compounds, YXJ-E1 ,and 7,4′-dihydroxyflavone, were isolated from the fermentation broth of Streptosporangium sp . Their structures were elucidated on the basis of spectral evidence. Compound 1 is a new one . Compounds 1 and 2 possess acetylcholinesterase inhibitory activities.