新疆维吾尔族、汉族前列腺增生症患者血清PSA、PSAD及前列腺体积比较

Comparison of serum PSA,PSAD and prostate volume of benign prostate hyperplasia patients in Uigurs and Han nationality of Xinjiang district

目的探讨新疆维、汉民族不同年龄段前列腺增生症患者血清PSA、PSAD及前列腺体积的差异及它们之间的相关性。方法总结5年来前列腺增生症住院患者,其中汉族150例,维吾尔族114例,在检查治疗前行放免法检测血清PSA,经腹超声测量前列腺体积,并分别计算患者的PSAD,按照不同年龄段进行血清PSA、PSAD及前列腺体积的比较。结果维、汉民族各年龄段血清PSA及PSAD差异无显著性(P＜0．05)。血清PSA及前列腺体积均随年龄增长而增高,且它们之间关系呈正相关。两民族前列腺体积在60岁组和80岁组差异显著(P＜0．05),维吾尔族明显高于汉族。结论两民族前列腺增生症患者间血清PSA、PSAD差异无显著性,且与前列腺体积一样随年龄增长而增高。PSAD是更可靠的诊断指标。

Objective To investigate the difference and correlation in serum PSA, PSAD and prostate volume of benign prostate hyperplasia （BPH） patients between Uigurs and Han nationality of Xinjiang. Methods Serum prostate specific antigen was detected by radioimmunoassay （RIA） before physical examination. Serum PSA and prostate ultrasonography through a suprapubic abdominal approach of 150 Han and 114 Uigurs nationality inpatients with BPH were assayed. Volume of prostate and PSAD were calculated separately. All the data in different age groups and nationalities were evaluated with statistical analysis. Results The difference in PSA, PSAD of Uigurs and Han nationalities was not significant in different age groups respectively. Meanwhile, there was an obviously positive correlation （P〈0.05） among PSA, prostate volume and age respectively. The prostate volume of Uigurs was significantly higher than that of Han in 60～ and 80～ age groups （P 〈 0.05）. Conclusion The difference in serum PSA is not statistically significant between Urgurs and Han nationality. PSAD is more stable factor than others in diagnosis of BPH.