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动态突变──一种新的致病遗传机理 被引量:3

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摘要 动态突变──一种新的致病遗传机理张思仲在人类基因组中存在大量的DNA重复序列,它们的生物学功能至今仍未阐明,在疾病的发生发展中也不曾被赋予它们特定的意义。虽然随着基因技术的发展,象小卫星、微卫星DNA这样具有高度多态性的短重复序列已广泛用于诊断和基因...
作者 张思仲
出处 《中华医学遗传学杂志》 CAS CSCD 北大核心 1996年第3期129-130,共2页 Chinese Journal of Medical Genetics
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  • 1鲁明,樊东升,李小英,梁国威,李英,张华纲,康德瑄,张俊,张捷,王晶.基因确诊的肯尼迪病两例临床与分子生物学特点[J].中华神经科杂志,2007,40(4):232-236. 被引量:34
  • 2Ohta M, Inoue H, Cottieelli MG, et al.The FHIT gene, spanning the chromosome 3p14. 2 fragile site and renal carcinoma- associated t (3 ; 8) breakpoint, is abnormal in digestive tract cancers. Cell,1996, 84: 587-597.
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