绿色硝解合成六硝基六氮杂异伍兹烷

Synthesis of CL-20 by Clean Nitration

以2,6,8,12-四乙酰基-2,4,6,8,10,12-六氮杂四环[5.5.0.03,11.05,9]十二烷(TA IW)为原料,利用绿色硝化剂五氧化二氮在硝酸介质中硝解制得CL-20。该方法通过改变硝化剂,不仅避免使用浓硫酸,而且原子经济性高,具有良好的环境效益。用元素分析、红外光谱、核磁共振、质谱等对其结构进行了检测和表征,并探讨了反应温度和反应时间对CL-20产率的影响。实验结果表明,当反应温度为0℃,反应时间为1 h时,CL-20的最佳产率达62%。

CL-20 was synthesized via nitrotion in nitric acid with 2,6,8,12-tetraacetylhexaazatetracyclo [5.5.0.0^3.11.0^5.9] dodecane （TAIW） and clean nitrating agent dinitrogen pentoxide. By the use of new nitrating agent, the reaction eliminated the use of concentrated sulfuric acid and was environmental friendly with high atom economy. The structure of the compound was characterized by elemental analysis, IR, NMR and MS. The effects of reaction temperature and reaction time on the yield were also investigated, showing that under the conditions of reaction temperature, 0℃ and reaction time, i h, the optimum yield of CL-20 was up to 62%.