良性假肥大型肌营养不良症患者肺功能的表现特点与康复对策

Pulmonary Function Characteristics and Rehabilitation Strategy for Becker Muscular Dystrophy

目的:探讨良性假肥大型肌营养不良症(BMD)患者的肺功能表现特点与康复对策。方法:测定12例BMD患者的肺通气功能并将数据进行统计学处理,分析其临床表现。结果:12例患者的肺通气功能主要指标均值均在正常范围,但1 s用力呼气容积与用力肺活量之比值(FEV1/FVC)较正常人群明显增高。结论:FEV1/FVC比例不协调是BMD患者肺通气功能的主要特点,其原因可能与呼吸肌尤其是主要吸气肌膈肌和主要辅助呼气肌腹肌肌力较弱有关,康复锻炼对改善FEV1/FVC比例的不协调有帮助,应列为BMD患者必做的康复训练。

Objective： To investigate the pulmonary function characteristics and rehabilitation strategy for Becker muscular dystrophy （BMD）. Methods： Pulmonary ventilation function of 12 patients with BMD was measured and analyzed. Results： The values of pulmonary ventilation function of the 12 cases were basically normal except for FEV1/FVC,Conclusion： FEV1/FVC in the patients with DMD is significantly higher than that of healthy population, while other pulmonary ventilation indices were in normal range. The elevated FEV1/FVC is probably due to the weakness of diaphragmatic muscle and the accessory respiratory muscles, Rehabilitation exercise aiming at the respiratory muscles may be helpful for improving the pulmonary function of BMD patients.