妊娠合并颅脑外科疾病11例临床分析

Clinical Analysis of 11 Cases with Pregnancy Associated with Encephalopathy

目的研究妊娠合并颅脑外科疾病的临床特点及其对母婴的影响,探讨合并颅脑外科疾病孕妇的妊娠结局。方法对1990年1月至2005年5月,11例妊娠期颅脑外科疾病患者的临床资料进行回顾性分析。结果11例妊娠合并颅脑外科疾病孕产妇死亡5例,存活6例;新生儿存活4例。结论妊娠可能促使瘤体生长或破裂,开颅手术同时应及时结束妊娠,分娩以剖宫产为宜,尽量同时行绝育术。不宜采取母乳喂养。

Objective To investigate the clinical characteristics, early diagnosis, preventive and therapeutic methods, and the effects on maternal and infant health of encephalopathy during pregnancy. Methods The clinical materials of 11 cases with pregnancy associated with encephalopathy in Tiantan hospital were analysed retrospectively. Results Pregnancy can accelerate the growth or rupture of cerebroma and encephalic angioma. Craniotomy was necessary as soon as possible. Caesarean section was the suitable delivery modus. We should focus on prevention and treatment of post-eclampsia cerebral infarction. Conclusion The high rate of misdiagnosis, quick development and high rate of death account for characteristics of encephalopathy during pregnancy. Regular antenatal examination, early diagnosis and just-in-time treatment are critical to improve the prognosis.