IPL作用下鼠皮形态改变的显微观察与初步分析

Morphologic Changes of Mouse Skin under Laser Scanning Confocal Microscopy after Irradiated by IPL in Early Stage

观察光子嫩肤(IPL)后鼠皮的形态学随时间的改变情况,如:表皮层、真皮层的增厚或变薄的情况。探讨IPL作用下,皮肤的表皮、真皮厚度变化与IPL在特定波长的能量密度的关系。以小白鼠作为研究对象,先去毛,用IPL在一定波长不同的能量密度照射活体小白鼠皮肤,分别在照射前、照射后,以及之后的1天,3天,7天应用激光共聚焦显微镜观察皮肤内部的结构,并对其不同的能量密度与照射前相比进行分析,讨论了真皮胶原蛋白在组织的修复过程的作用及其中的关键因素。

The morphologic changes of mice skin after being irradiated by IPL were observed by a laser scanning confocal microscopy. The relation of the epithelial or dermal interaction with the intensity pulsed light （IPL） in different energy density was discussed. A mouse was chosen and moulted, and then irradiated by the IPL system in vivo under certain wavelengths with different energy densities. The morphologic changes of mouse skin were observed before and after （ lday, 3days, 7days） irradiated respectively. The results were compared and analyzed. The function of dermal collagen during the renovating of the tissue was studied and the key factors were＇presented.