摘要
目的:研究大花红景天正丁醇提取物(W)的抗氧化作用及其机制。方法:测定对FeSO4/Cys氧化体系致肝微粒体脂质过氧化的抑制率、对H2O2引起红细胞溶血的抑制效果和清除DPPH自由基实验。结果:50μg/m lW对肝微粒体脂质过氧化的产物MDA生成有明显的抑制作用;对过氧化氢引起氧化溶血有抑制作用;对DPPH自由基也有一定的清除作用。结论:大花红景天具有一定的抗氧化能力。
Objective： To study the antioxidative offect and its mechanism of Rhodiola n-butanol extract. Method： Inhibition rates of liver microsome lipid peroxidation caused by FeSO4/Cys were measured. Inhibition rates of haemolysis caused H2O2 were measured. DPPH free radical scavenging capacity was assayed. Result： Rhodiola n-butanol extracts can inhibit the liver microsome lipid peroxidation caused by FeSO4/Cys, haemolysis caused H2O2. DPPH radical was scavenged by Rhodiola n-butanol extracts. Conclusion： Rhodiola has an antioxidative effect.
出处
《中药药理与临床》
CAS
CSCD
北大核心
2006年第3期118-120,共3页
Pharmacology and Clinics of Chinese Materia Medica
基金
创新药物筛选技术平台
863重大专项
No2004AA2Z3782西部之光专项
关键词
大花红景天
抗氧化
溶血
自由基
Rhodiola herb
antioxidative
haemolysis
fyee radicie
