摘要
目的研究冠心病(CHD)患者血清高敏C反应蛋白(hs-CRP)和脑钠肽(BNP)浓度在治疗前后的变化,探讨其临床应用价值。方法测定93例CHD患者的BNP和hs-CRP浓度,同时检测其中25例不稳定型心绞痛(UAP)经皮冠状动脉成形术后的BNP和hs-CRP浓度,并与30名正常对照比较。结果CHD患者与正常组比较,hs-CRP和BNP水平均有极显著性差异(P<0.01);BNP和hs-CRP水平在UAP治疗前后有极显著性差异(P<0.01)。结论BNP和hs-CRP对于冠心病的诊断具有重要意义,并可作为CHD疗效观察的一个重要参数。
Objective To study serum high sensitive C-reactive protein（hs-CRP） and brain natriuretic peptide（BNP） levels in patients with coronary heart disease（CHD） and to explore the values in CHD. Methods The levels of serum hs-CRP and BNP from 93 CHD patients were measured and hs-CRP and BNP levels of 25 unstable angina pectoris（UAP） patients after PT- CA were also measured comparing with 30 healthy individuals. Results The levels of serum hs-CRP and BNP were significant differences between the CHD group and healthy group（P〈0. 01） ;The levels of serum hs-CRP and BNP in UAP patients were decreased significantly after therapy（P〈0. 01）. Concusioa BNP and hs-CRP are very important to diagnose the CHD and may be considered as the therapy effect observing markers.
出处
《华中医学杂志》
CAS
2006年第3期257-258,共2页
Central China Medical Journal
关键词
C反应蛋白
冠心病
脑钠肽
C-reactive protein
Coronary heart disease
Brain natriuretic peptide
