秀丽莓(Rubus amabilis Focke)镇咳祛痰作用初探

Preliminary Study on Relieving Cough and Eliminating Phlegm of Rubus Amabilis Focke

目的:观察秀丽莓的镇咳祛痰作用.方法:秀丽莓水提液灌胃给药,小鼠浓氨水引咳法观察秀丽莓的镇咳作用,小鼠气管段酚红排泌量法观察秀丽莓的祛痰作用.结果:与空白对照组相比,秀丽莓水提液(80g生药/kg体重)可明显减少小鼠咳嗽次数,对潜伏期无影响;20g生药/kg体重的秀丽莓水提液对小鼠气管段酚红排泌量无显著性影响.结论:大剂量秀丽莓水提液有镇咳作用,祛痰作用不显著.

Objective：to observed the relieving cough and eliminating phlegm actions of Rubus amabilis Focke （RaF）. methods： The water extraction of RaF was administered by igto mice. The effects of RaF on the frequency of cough and latent period of cough induced by ammonium hydroxid in mice, on the excretion quantity of phenoful - phthalein in trachea of mice were observed. Results： Compared with control group, the extraction of RaF （80g crude drugs/kg body weight） could obviously decrease the frequency of cough, and could not prolong the latent period of cough. The little dosage of RaF extraction （20g crude drugs/kg body weight） could not markedly increase the excretion quantity of phenoful - phthalein in trachea of mice. Conclusion： the water extraction of RaF has obviously relieving cough, and no eliminating phlegm effect to mice.