摘要
目的通过正交试验法考察养血扶正颗粒的水提制备工艺。方法以阿魏酸的含量作为考核指标,通过L9(34)正交试验设计考察水提醇沉的制备工艺条件,确定养血扶正颗粒的最佳制备工艺。结果水提醇沉制备工艺影响因素大小依次是:煎煮时间(C)>加水量(A)>醇沉浓度(D)>煎煮次数(B),最佳制备工艺条件为A3B3C1D1,即处方药材加10倍量水,煎煮3次,每次0．5 h,醇沉浓度40％。结论该提取工艺合理可行,有效成分提取较为完全。
Objective To investigate the preparing procedures of Yangxuefuzheng granules. Methods Using the content of ferulic acid as index, the optimum extraction conditions of Yangxuefuzheng granules was studied with the orthogonal test of L9（3^4）. Results The influencing power of factor were described as： C 〉 A 〉 D 〉 B（A： added water volume, B： decoction times, C： decoction frequency, D： precipitating concentration of alcohol）. The optimizing preparation conditions were A3B3C1D1, i.e. added 10 times water, decoction for 3 times, 0.5 hour every time and added alcohol to 40%. Conclusion The optimum extraction procedures are rational, feasible, and the extraction rate of active components is good.
出处
《兰州大学学报（医学版）》
CAS
2006年第2期56-58,共3页
Journal of Lanzhou University（Medical Sciences）
基金
甘肃省科学事业费(QS041-C33-13)资助项目。
关键词
养血扶正颗粒
正交设计
制备工艺
阿魏酸
Yangxuefuzheng granules
orthogonal design
preparing procedure
ferulic acid
