疏血通注射液治疗椎-基底动脉供血不足引起眩晕急性发作的临床研究

A Clinical Study of Shuxuetong Injection for the Treatment of Acute Vertigo Induced by Vertebrobasilar Artery Insufficiency

目的:观察疏血通注射液治疗椎-基底动脉供血不足引起眩晕急性发作的临床疗效。方法:将88例患者随机分为2 组各44例。治疗组采用疏血通注射液治疗;对照组采用丹参注射液加盐酸氟桂利嗪胶囊治疗。疗程均为1周。主要观察临床疗效及起效时间、治疗前后平均血流速度的变化。结果:临床治愈率治疗组为72．73％,对照组为45．45％,2组比较,差异有非常显著性意义(P<0．01)。起效时间<24h治疗组38例,对照组20例,2组比较,差异有显著性意义(P<0．05)。2组治疗后平均血流速度明显加快,与治疗前比较,差异均有非常显著性意义(P<0．01);治疗后治疗组与对照组比较,差异有非常显著性意义(P <0．01)。结论:疏血通注射液治疗椎-基底动脉供血不足引起急性眩晕发作,起效快,疗效较好,作用安全。

Objective： To observe the clinical effect of Shuxuetong Injection （SI） for acute vertigo （AV） induced by vertebrobasilar artery insufficiency （VBAI）. Methods： 88 cases were allocated to 2 groups randomly （each group 44 cases）. The treatment group was treated by SI. The control group by Salvia Miltiorrhiza Injection and Flunarizine Hydrochloride Capsule. One week constituted the course of treatment. The initial effective time, clinical symptoms and the changes of transcranial Doppler sonography were observed, Results： The cured rate was 72.7% and 45.45% in treatment group and control group respectively （P 〈 0.01）. The initial effective time was 〈 24h in 38 cases of treatment group and 20 cases of control group （ P 〈 0. 05）. After treatment, the average blood flow speed in both groups were marked accelerated as compared with before treatment （P 〈 0.01）, and its difference between treatment group with control group was very significant （ P 〈 0.01）. Conclusion： ST exerts a rapid, safe and good effect for AV induced by VBAI.