棕榈酸单乙醇酰胺葡萄糖苷的合成研究

Study on the Synthesis of Palmitic Acid Monoethanolamide Polyglycoside

以棕榈酸和单乙醇胺反应,生成棕榈酸单乙醇酰胺,再与丁苷进行转苷化反应,得到文献未曾报到过的棕榈酸单乙醇酰胺葡萄糖苷非离子表面活性剂。合成丁苷的适宜条件:丁醇和葡萄糖物质的量之比6∶1,催化剂和葡萄糖物质的量之比0.03∶1,反应时间3 h,温度120℃;合成棕榈酸单乙醇酰胺葡萄糖苷的适宜条件:棕榈酸单乙醇酰胺与丁苷物质的量之比1∶1,反应温度145℃,反应时间1 h。

Palmitic acid monoethanolamide（PMEA） was synthesized by the reaction of pahnitic acid with monoethanolamine. The nonionie surfactant palmitic acid monoethanolamide polyglycoside（ PMEAPG）,which has not been reported in the literature, was obtained by transglycosidation of PMEA with n-butyl glycoside. The suitable synthesis conditions of PMEA were： molar ratios of n-butyl to glucose and catalyst to glucose 6 ： 1 and 0.03 ： 1 respectively, reaction temperature 120 ℃, reaction time 3 h. Suitable synthesis conditions of PMEAPG were： molar ratio of PMEA to n-butyl glycoside 1 ： 1 ,reaction temperature 145 ℃, reaction time 1 h.