妊娠糖尿病筛查与妊娠糖尿病母儿结局的临床分析

Clinical analysis of screen method for gestational diabetes mellitus(GDM) and fetal outcome in pregnancy with GDM

目的：在我区妇幼保健院系统开展妊娠糖尿病的筛查，调查其患病率及妊娠糖尿病血糖控制对妊娠结局的影响。方法：2004年1月-2005年6月，对在我区妇幼保健院建档的孕妇，在孕24-28周进行妊娠糖尿病的筛查，调查患病率。并追踪诊断妊娠糖尿病患者的孕期血糖控制良好（A）组与血糖控制不良（B）组，对母儿结局的影响，两组进行比较。结果：妊娠糖尿病患病率为2．64％，B组的妊高征、早产儿、先兆子痫、胎死宫内等的发病率较A组明显增高，有显著差异。B组的新生儿畸形、新生儿红细胞增多症及低体重儿均较A组明显增高，有显著差异。结论：加强糖尿病孕妇孕期的血糖控制，可减少孕产妇的合并症。

Objective： To study the incidence of gestational diabetes mellitus （GDM） in women and children＇s health hospital nanshan area in shenzhen and the relationship between blood glucose level and pregnancy outcome. Methods： Clinical data of pregnant women who had antenatal care and delivered in women and children＇s health hospital nanshan area in shenzhen from Jan 2004 to Jun 2005 were analyzed in order to prospectively study the incidence of GDM. All of them underwent screening of blood glucose treatment in gestational week 24-28. Among them, the women with GDM were divided into two groups （ groupA , B） according to the glucose level. The maternal and fetal outcomes of the two groups were compared. Results： The rate of pregnant outcomes was 2, 64 %. 2 cases of fetal death in group B, but no case of fetal death in group A （ P = 0, 024） . The rate of pregnancy induced hypertension and premature labor and preeclampsia in group B were significantly higher than those in group A. . The rate of new born malformation and new born erythrocytosis and low birth weight infant in group B were significantly higher than those in group A, Conclusion： Maternal blood glucose with ideal control throughout pregnancy may reduce the maternal complications in GDM.