辐照含碘骨抗菌性能的实验研究

The Experimental Study of Antimicrobiologic Effect of Radiated Bone Incoporated with Lodophors

目的:本研究观察了辐照含碘动物骨、人骨抗菌性能。方法:临床中收集的骨和动物兔骨生理盐水冲洗,无菌包装,送10万级超净层流工作室处理,贮存方法有含碘辐照、辐照、深低温处理,对比3种骨不同贮存时间抗菌性能情况,同时观察动物骨同种移植后的组织反应。结果:3种贮存方法中,仅辐照含碘骨有明显的抗菌性能,移植后周围炎性反应轻。结论:辐照含碘骨有抗菌性能,移植后炎性反应轻。

Objective. To observe antimierobiologie effect of radiated bone incoporated with iodophors. Methods. The bones collected from human and rabbit were rinsed with PBS and aseptic parceled,followed by be treated in superclean-laminar flow room and stored as three groups below：Group A.the radiated allogeneic bone incorporated with iodophors;Group B：radiated allogeneic bone group; and Group C：deep frozen allogeneic bone group. They were assayed by bacterium culture and inhibiting bacteria in vitro. Results-There were bacterial growth in GroupsB and C. By contrast, bone grafts of Group A effectively inhibit growth of bacteria（P^0. 01）. Conclusion： Radiated allogeneic bone incorporate with Iodophors should have good antimicrobiologic effect and it can avoid contamination.