自主神经对冠状动脉搭桥术后心房颤动的影响

Autonomic Nervous Activity in Patients with Atrial Fibrillation after Coronary Artery Graft Surgery

目的:通过心率变异性(heart rate variability,HRV)分析,探察CABG术后的自主神经活性对发生AF的作用。方法:对CABG术后发生AF的20例患者进行24 h动态心电图记录,并进行HRV时域、频域分析,同时设年龄、性别、一般临床特征相匹配的CABG术后非AF(NAF)患者为对照。结果:AF组心率明显快于NAF组。HRV各时域、频域指标两组比较无统计学意义。结论:交感神经过度激活可能是CABG术后AF发生的机制之一。

Objective：To examine the effect of autonomic nervous activity on Atrial fibrillation（AF） after coronary artery bypass graft surgery（CABG）by heart rate variability analysis. Methodes： Twenty-four hours ambulatory ECG monitoring and HRV analysis were performed in 20 patients with postoperative AF. These data were compared to 67 controls who did not develop postoperative AF but did have matched sex-and age. Results： Heart rate increased significantly in patients with postoperative AF. There was no significant difference in time and frequency domain HRV measures between AF patients and non-AF patients. Conclusion： Overactivation of sympathetic nervous system might be one of the pathophysiological mechanism of onset of AF after CABG surgery.