网织红细胞参数在儿童血液病中的应用

Application of reticulocyte parameters in children's blood diseases

目的:探讨网织红细胞参数在儿童血液病中的临床应用价值。方法:应用SysmexXE-2100全自动血细胞分析仪检测106例儿童血液病患儿的网织红细胞计数(RET#)、网织红细胞百分比(RET)、未成熟网织红细胞比率(IRF)、低荧光强度网织红细胞比值(LFR)、中荧光强度网织红细胞比值(MFR)、高荧光强度网织红细胞比值(HFR)等参数。结果:营养性缺铁性贫血、溶血性贫血、血小板减少性紫癜患儿RET、IRF等指标显著增高(P<0.05),再生障碍性贫血、白血病患儿RET#显著降低(P<0.05),IRF显著增高(P<0.05)。结论:测定网织红细胞及其相关参数有助于判断骨髓生成红细胞的活动度,对贫血类型的鉴别诊断有实用价值。

Objective To study the clinical value of reticulocyte parameters in children＇s blood diseases detected by Sysmex XE-2100 automatic blood analysor. Methods Reticulocyte absolute value（RET#）,reticulocyte percentage（RET）, immature reticulocyte formation（IRF）,low scattered light intensity reticulocyte percentage（LFR）, middle scattered light intensity reticulocyte percentage （MFR） and high scattered light intensity reticulocyte percentage （HLR） of 106 cases in-patients＇ blood sample were detected by Sysmex XE-2100 automatic blood analysor. Results In the groups of IDA,HA and ITP,RET# and IRF were notably higher than those of control group（P〈0.05）. In the groups of AA and leukemia, RET# were notably lower than those of the control group（P〈 0.05）, but IRF was notably higher than that of the control group （P〈O.O5）.Conclusion The detection of reticulocyte and its parameters will help decide the activity of red blood cell,and it has important practical value in diagnosis of anemia type.