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鼠源单克隆抗体人源化研究进展 被引量：4

Advances in the Studies of Humanization Mouse Monoclonal Antibody
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摘要 杂交瘤技术诞生以来,鼠源单克隆抗体为人类疾病的研究起到了重大的推动作用,而鼠源单克隆抗体用于疾病的治疗时却有严重的不足,单克隆抗体人源化已是当前研究的热点。对单克隆抗体人源化的有关实验研究进展进行了综述。 mouse monoclonal antibody have greatly impacted the development of research on human disease since traditional hybridoma techniques publication, but which have serious shortage in the treatment of diseases. Now, monoclonal antibody humannization has attracted significant research. In this review,the recent advance in the experimental studies on monoclonal antibody humannization,
作者 王臣 温文彦 张春杰
机构地区 河南科技大学动物科技学院
出处 《安徽农业科学》 CAS 北大核心 2006年第11期2336-2337,2343,共3页 Journal of Anhui Agricultural Sciences
基金 河南科技大学青年基金项目(2004QN007) 人才基金项目(04044)
关键词 单克隆抗体 抗体人源化 基因工程 Monoclonal antibody Antibody humanization Genetic engineering
分类号 Q789 [生物学—分子生物学]
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参考文献13

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安徽农业科学
2006年 第11期

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