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系统性红斑狼疮142例临床分析 被引量:4

Clinical Analysis of 142 Cases of SLE
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摘要 目的探讨系统性红斑狼疮(SLE)患者的临床特点。方法对142例SLE患者外周血象、实验室免疫检查结果及主要临床表现进行总结分析。结果142例中血象异常者121例,其中贫血79例,血小板减少65例,白细胞减少76例,二系减少者69例,全血细胞减少15例,给予糖皮质激素及(或)免疫抑制剂治疗后血象有显著改善(P<0.01〉。血细胞减少组抗dsDNA、补体C3、C4、24 h尿蛋白、肾损害、浆膜炎与血细胞正常组比较有统计学意义(P<0.05)。结论SLE易并发血液系统损害,表现多样,经糖皮质激素及免疫抑制剂治疗,其外周血和骨髓象均有不同程度的改善。血细胞减少组抗dsDNA、补体C3、C4、24 h尿蛋白、肾损害、浆膜炎与血液系统受累明显相关,补体C3可作为判断SLE病情复发及缓解的一个敏感而可靠的指标。
出处 《中国皮肤性病学杂志》 CAS 北大核心 2006年第6期351-352,共2页 The Chinese Journal of Dermatovenereology
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