甲状腺微小癌不同术式的临床疗效观察

Investigate the Therapeutic Efficacy of Different Operation Styles in Patients with Thyroid Micarocarcinoma

[目的]探讨甲状腺微小癌不同手术方式治疗对临床疗效及预后的影响。[方法]回顾性分析190例甲状腺微小癌的临床资料,手术方式,随访情况。[结果]不同手术方式对生存率无明显影响,但对复发,转移,无瘤生存关系密切,34例再次手术患者原因为残叶复发3例,对侧叶发病3例,同侧颈部淋巴转移28例,而首次行腺叶+峡部切除+中央组淋巴清扫组同颈淋巴功能颈清组疗效相仿,5年无瘤生存率100%。[结论]甲状腺患侧叶全切+峡部切除+中央组淋巴清扫对甲状腺微小癌治疗效果满意,可作为规范术式推广。

[Objective]To investigate the effect of different operation styles on the therapeutic efficacy and prognosis in patients with thyroid microcarcinoma. [Methods] The clinical data, different operation styles and followed data of 190 cases with thyroid microcarcinoma from 1990 to 2004 were retrospectively analyzed. [Results]The different operation styles of patients have no singnificant correlation with survival rate, but have significant correlation with tumor recurrence, tumor metastasis and no tumor survival, In 34 cases operated again,there are 3 cases of remainder lobe＇s recurrence,3 cases of opposite lobe recurrence and 28 cases of neck lymph node metastasis; the experience group of total lobectomy and isthmas of thyroid dissected and central node dissection in the first time has simiar effcacy with the contral group of functional lymph mode dissection,and the non-tumor survival in 5 years is 100%. [Conclusion]Ill lobe total lobectomy and isthmas of thyroid dissected and central node dissection have satisfactory efficacy in treatment of thyroid microcarcinoma and may be known as a kind of advisable operation.