早产儿坏死性小肠结肠炎的临床分析

The Clinical Features of Necrotizing Enterocolitis in Prematures

目的：了解早产儿坏死性小肠结肠炎(NEC)的临床特点,探讨及时诊断和防治早产儿NEC的方法。方法：分析32例早产儿NEC的临床表现、影像学特点、病程发展、预后,并与27例足月儿NEC进行比较。结果：早产儿NEC更多表现为反应差(46.9%)、胃纳差(34.4%),肠穿孔率(21.9%),明显高于足月儿组；病死率(28.1%)也高于足月儿组(3.7%)。结论：与足月儿比较,早产儿NEC临床表现中以反应低下和纳差比较突出,穿孔发生率高,病死率也比较高。

Objective：To investigate the relationship between clinical features and prognosis of necrotizing enterocolitis in premature. Methods：This was a cohort study. From Aug. 1999 to Apr. 2005 ,the medical records of patients with necrotizing enterocolitis NEC in Children＇s Hospital of Fudan University were analyzed. 32 prematures and 27 term infants were enrolled in this study by comparing by clinical manifestation,feature of imaging,course of disease and prognosis. Results：Prematures had lower reaction （46. 9%） ,worse appetite（34. 4%） and higher rates of perforation（21, 9%） than those of infatns, Conclusion： Prematures with NEC had lower reactions and worse appetite than those of term infants. The rates of perforation and mortality in prematures with NEC are higher than those in term infants with NEC.