氯诺昔康用于妇科术后静脉自控镇痛的临床观察

Clinical Observation of Xafon Hydrochloride in Intravenous Patient Control Analgesia

目的：评价氯诺昔康用于手术后静脉自控镇痛的临床效果。方法：选择100例妇科病人随机分为两组：芬太尼组(n =50)和氯诺昔康组(n=50)。两组镇痛泵配方均不加任何止吐药及其它辅助药物。镇痛效果评估采用VAS(视觉模拟)评分法,分别观察手术后4,8,12,24,48 h的VAS评分,0为无痛,1～3为满意,3～5为基本满意,大于6为不满意,10为无效。同时观察两组的不良反应发生率。结果：芬太尼组VAS评分与氯诺昔康组大致相似,但前者的不良反应发生率明显高于后者。结论：两组均有较满意的术后镇痛作用,但芬太尼组的不良反因发生率明显高于氯诺昔康组。

Objective：To evaluate the efficacy and safety of the Xafon Hydrochloride in patient control analgesia. Methods：100 gynecologic patients were divided randomly into two groups, Fentanyl group（n= 50） and Xafon group（n = 50）. The VAS （visual analog score） of the two groups with postoperative 4, 8, 12, 24, 48 hours and adverse effects were observed. Results;VAS of Fentanyl group was higher than that of Xafon group and the adverse effects were more common than those in Xafon group. Conelusion..In both groups, patient control analgesia can be satisfied, but there is considerably lower adverse effect in group two than in group one.