冠状动脉内支架植入术后再发胸痛原因分析

Analysis of Causes of Relapsed Chest Pain After Coronary Stent Placement

目的:探讨冠状动脉支架植入术后再发胸痛的原因,并观察导致支架内再狭窄的影响因素。方法:对我院行冠状动脉支架植入术后患者随访,对28例再发胸痛者行冠状动脉造影复查。结果:无狭窄13例,支架内再狭窄者15例。应用Logistic多因素逐步回归分析法,分析两组患者的临床特点及随访期间用药情况与再狭窄的相关性。发现血清胆固醇和脂蛋白Lp(α)水平增高是支架内再狭窄的重要独立危险因素。结论:冠状动脉支架植入术后不稳定心绞痛是支架内再狭窄常见临床表现。必须重视并尽可能消除导致支架内再狭窄的因素,调脂应是重要的治疗措施。

Objective：To analyze the causes of relapsed chest pain and risk factors of restenosis after coronary stenting. Methods, Twenty-eight patients with relapsed chest pain after coronary stenting were followed up by angiography. Results, Thirteen cases showed no stenosis and 15 cases present restenosis. The correlation between clinical characteristics and follow-up medications and restenosis in 2 groups were analyzed by logistic regression. The results revealed that increased level of cholesterol and lipoprotein a was the main risk factor of restenosis. Conclusion, Unstable angina after stenting is an usual manifestation of restenosis. We must pay attention to it and eliminate the risk factors of restenosis. Lowering lipids is an important therapeutic measure.