早期乳腺癌保乳治疗疗效分析(附45例报告)

Analysis of Clinical Outcome in Early-stage Breast Cancer Patients Treated with Breast-conserving Therapy

目的观察和分析早期乳腺癌保乳治疗的疗效和不良反应。方法对45例早期乳腺癌行保乳手术;术后31例接受了放疗及化疗,8例只进行了放疗,3例只行了化疗,放化疗均未做的3例。结果 45例术后存活时间为6-126个月。31例术后行放化疗的患者目前均存活,无瘤生存率81％;8例术后仅行放疗的患者中1例术后3年死于远处转移,2例已发现远处转移(骨转移和肝、肺转移),无瘤生存率63％; 3例术后放化疗均未做的患者中1例第5年出现局部复发;3例只行化疗的患者中1例第4年出现局部复发;其余患者均存活,未见转移及复发。全组无放射性溃疡及感染发生,未见切口愈合延迟;2例出现放射性肺炎、胸膜炎,经对症治疗后症状缓解;1例出现心包炎,经治疗后治愈;1例保留乳房部分皮肤萎缩和硬化。结论早期乳腺癌保乳治疗的疗效良好,合理的放化疗可以使保乳治疗的并发症得到有效地控制。

Objective To evaluate the clinical effectiveness and side-effect in early-stage breast cancer patients treated with breast conserving therapy. Methods Analyzed 45 patients with primary breast cancer who underwent breast conserving therapy.After operation 31 cases received radiotherapy and chemotherapy, 8 cases received only radiotherapy, 3 cases received only chemotherapy and 3 cases did not receive radio-chemotherapy.Resuits Survival time of all patients was 6 to 126 months. Amomg 45 cases, 1 cases who refused the chemotherapy died of metastasis.Metastasis was also found in 3 cases,2 of whom refused chemotherapy. Local recurrence was found in 2 cases who did not take the radiotherapy. Conclusion With the equitable radiotherapy and chemotherapy after operation, berast-conserving therapy may benefit early-stage breast cancer patients and the complications caused by it can be effectively controlled.