血吸虫中间宿主的研究进展

The progress of researches on the intermediate host of schistosome

近年来,在WHO倡导的血吸虫病二元化防治策略的指导下,血吸虫中间宿主的研究日渐深入,研究者力求从分子生物学水平阐述其遗传、进化、生物地理分布、生殖、免疫、代谢、诊断机制,探求其如何成为血吸虫的适宜中间宿主。随着全球经济技术的不断发展,遥感技术为监测血吸虫病的流行提供便捷服务,但大型水利建设项目为血防工作带来不确定影响,其长期效应仍在观测之中。在灭螺方面,高效低毒的化学灭螺药在继续筛选中,生物灭螺和无害化钉螺的研究进展值得关注。该文主要对血吸虫中间宿主的最新研究进展作一综述。

Recently, with the deep and systematic researches on the intermediate host of schistosome under the supervision of the dual strategy of WHO, specialists try to explore the mechanisms of heredity, evolution, bio-geographical distribution, reproduction, immunity, metabolism and diagnosis at the level of molecular biology to reveal why snails become the adequate intermediate host of schistosome. The advanced remote sensing technology facilitates controling the prevalence of schistosomiasis, but big dam project brings uncertain impacts for control program. In addition, molluscicides with high efficacy and low toxicity are under investigation while the studies on biomolluscicides and harmless snails deserve more attention. This article reviews recent progress on researches on schistosome＇s intermediate host.