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胸腹部创伤患者早期外周血中IL-12水平变化及临床意义

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摘要 采用双抗体夹心酶联免疫吸附法检测68例胸腹部创伤患者外周血IL-12水平,并与30例健康者作对照。结果高创伤严重度评分(ISS)组外周血IL-12水平与较低ISS组相比明显增高,且均高于正常对照组。伤后并发全身炎症反应综合征(S IRS)和多器官功能不全综合征(M ODS)患者外周血中IL-12水平较未并发S IRS和M ODS者显著增高。认为胸腹部创伤患者伤后早期外周血中IL-12的水平与损伤严重程度相关,其检测对伤情的判断具有重要意义,对创伤后机体并发S IRS和M ODS有重要预测价值。
机构地区 聊城市人民医院
出处 《山东医药》 CAS 北大核心 2006年第18期46-47,共2页 Shandong Medical Journal
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