综合康复训练改善阿尔茨海默病患者认知功能障碍的研究

Study on the effect of comprehensive rehabilitation training in patients with Alzheimer disease

目的 探讨有效的阿尔茨海默病（AD）患者认知功能的康复训练方法.方法 将80例早中期AD患者随机分为2组.对40例实验组患者进行为期1年的康复训练,包括智能、自理能力和体能训练,突出个体化训练;40例对照组患者仅接受常规措施.训练前后采用MMSE量表每3个月评定1次.结果 训练9～12个月后实验组MMSE总均分显著高于对照组（P＜0.05）;1年后实验组的“定向力”和“语言能力”得分与对照组相比差异有统计学意义（P＜0.05）.结论 综合康复训练可有效促进患者认知功能的改善,值得推广应用.

Objective To study effective way of rehabilitation training for patients with Alzheimer＇s disease. Methods 80 AD patierts at early and middle stages were randomized into two groups： experimentalgroup （n = 40） and control group （n = 40）. Patients in the experimental group received oneyear rehabilitation training, including individuated trainings of intelligence, self-care and physical ability, and those in the control group were treated with routine. All the patients were evaluated every 3 months with MMSE before and after training. Results The total scores of MMSE in the experimental group were significantly higher than those in the control group （P 〈 0.05） after 9- 12 months＇ training; After 1 year＇s training the scores of orientation and language were significantly different from those in the control group （P 〈 0.05）. Conclusions Comprehensive rehabilitation training can improve AD patients＇ cognitive function and could be used widely.