摘要
为探讨CD16+56抗原在急性髓系白血病(AML)中的表达及其临床意义,本文用流式细胞仪检测42例AML患者的骨髓细胞,分析其细胞形态学(FAB)分型、免疫表型和临床特点。结果显示:42例AML患者中CD16+56阳性7例(16.6%),1例部分表达(2.4%),34例没有表达(80.9%)。CD16+56阳性的AML患者中,FAB分型、免疫表型和临床表现各有特点,多见于M2、M5,髓外浸润常见,大多数预后不良。
To evaluate the expression and clinical signification of CD16＋56 in acute myelogenic leukemia（AML）, myelocytes of 42 patients with AML were measured by flow cytometry, and the morphology, immunophenotype and clinical features were analyzed. Seven of 42 （16. 6%）cases expressed CD16＋56 positivly, 1/42（2.4%） expressed partly, and 34/42 （80. 9%） expressed CD16＋56 negatively. From the results it could be concluded that the FAB types, immunophenotype and clinical features of AML with positively expressed CD16 ＋ 56 were varied. The involvement of medullary was common and the prognosis was poor in the patients with M2 or M5.
出处
《标记免疫分析与临床》
CAS
2006年第2期83-84,87,共3页
Labeled Immunoassays and Clinical Medicine
