摘要
以γ射线照射减弱日本血吸虫尾蚴接种免疫小白鼠。致敏后再以尾蚴攻击感染动物，同时以尾蚴感染未致敏小白鼠作为对照组。４５ｄ后解剖两组动物并以图象分析仪测量其肝内虫卵肉芽肿面积的比例。经统计学分析有明显差异（Ｐ＜０．０１）。提示以照射减毒活虫苗防治日本血吸虫病，保护人类健康似可实现。
The paper reported the results of study on morphometry of egg granulomas of schistosoma japonicum in mice with experimental and control groups. Mice were vaccinated with cercariae exposed to Co￣(60) for 34 days challenged with normal cercariae in experimental group. Only normal cercariae was used in the control group. It was noted the mean size of egg granuloma of experimental group was smaller than that of control group. Total collagenous fiber of egg granuloma and area of egg granuloma in experimental group decreased more than that of control group. The result had significant difference according to statistical analysis.
出处
《中国寄生虫病防治杂志》
CSCD
1996年第3期192-193,共2页
Chinese Journal of Parasitic Disease Control
基金
冶金工业部自然科学研究基金
关键词
日本血吸虫病
胶原纤维
虫卵肉芽肿
形态计量
Schistosoma japonicum, collagenous fiber, egg granuloma, morphometry
