微电流探测仪术中诊断肿瘤101例

Application of microcurrent detector to intraoperative diagnosis of 101 cases of tumor

目的:使用1种微电流探测仪观察恶性肿瘤与Na+微电流的关系,探索术中准确快速诊断肿瘤的新方法。方法:采用微电流探测仪,根据仪器操作规程对101例肿瘤组织进行检测,检测部位包括肿瘤组织表面和切面,同时检测肿瘤组织周围的正常组织和淋巴结作为自身对照,比较肿瘤组织和其周围正常组织微电流的变化。此外,对肿瘤组织进行病理学检查,明确其病理诊断。结果:97例肿瘤组织与其周围正常组织Na+微电流有明显的差异,肿瘤组织Na+微电流均超过30μA,最高者达到60～70μA,正常组织多在20μA左右,无1例超过30μA。微电流探测仪检测结果与常规病理诊断符合率为96%。结论:运用微电流探测仪术中检测肿瘤组织微电流来判断肿瘤的良/恶性,具有快速、简捷、准确的特点,有临床应用前景。

Objective To investigate the relationship of tumor malignancy with Na＋ microcurrent measured by microcurrent detector in order to develop a novel approach for rapid intraoperative diagnosis of tumor. Methods 101 cases of various tumors were studied. Na＋ microcurrent of tumor tissue or surrounding normal tissue was measured by Na＋ microcurrent detector. All tumor tissues were sampled for histopathological examination as well. Results In 97 cases （96%）, the Na＋ microcurrent level in tumor tissue was significantly different from that in surrounding normal tissue. It was greater than 30μA in tumor tissue with the maximum of 60 - 70μA, and averagely 20μA in surrounding normal tissue. The consistency of Na＋ microcurrent detection and pathological examination was 96%. Conclusion the measurement of Na＋ microcurrent by microcurrent detector is rapid , convenient and accurate, which may become a novel approach for rapid intraoperative diagnosis of tumor malignancy.