2004年德州市部分中学新生乙型肝炎感染状况调查

Investigation on Infection Situation of Hepatitis B of some Middle School Students in Dezhou in 2004

[目的]了解德州市中学生乙型肝炎病毒感染情况及免疫水平,提供中学生乙肝防治措施的依据。[方法]2004年9～10月对11076名初、高中新生采用酶联免疫吸附试验进行乙肝标志物(HBsAg、抗HBs、HBeAg、抗HBe、抗HBc)检测。[结果]HBsAg阳性率为4.74%,其中城乡学生差异无统计学意义(P>0.05),男女生、初高中生间的差异均有统计学意义(P<0.01);抗HBs阳性率为61.34%,城乡学生、男女生、初高中生间的差异均有统计学意义(P<0.01)。[结论]德州市中学生乙肝病毒感染率较低,抗HBs阳性率较高,但传染性较强的“大三阳”、“小三阳”比例亦较高,仍应重视乙肝的监测与防治工作。

[Objective]To understand the infection situation of hepatitis B virus and immunity level among middle school students in Dezhou,and provide basis for prevention and control of hepatitis B（ HB）. [Methods]To test HBsAg, Anti-HBs,HBeAg,Anti-HBe and Anti-HBc for 11 076 students by ELISA from September to October, 2004. [Results] HBsAg＇s positive rate was 4.74% ,and the difference between town and country （ P〉0. 05） had no statistic significance, but the differences between boys and girls, junior high school and senior high school （ P〈0. 01） had statistic significance. Anti-HBs positive rate was 61.34%, and the differences between those 3 pairs of groups all had statistic significance （ P 〈0.01）. [Conclusion]The infection rate of HB was lower and Anti-HBs positive rate was higher in Dezhou than other cities,but ratio of ＂big three positive＂ and ＂small three positive＂ was also high,so much more attention should be paid to surveillance and prevention on HB.